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Vitamin B6 to Treat Luteal Phase Defect?

Lori Ramsey


If I had to choose just one vitamin to take to help with my fertility, I'd choose vitamin B6. Vitamin B6 is also known as pyridoxine, and is water soluble. It can be found in yeast, whole grains, legumes, liver, eggs, cereal, meat and fish. Of course, all vitamins work together, and do well to keep a body healthy. However, vitamin B6 goes one step beyond--it helps with fertility. More than helping with fertility, it also helps with PMS.

Helping with premenstrual syndrome (PMS) symptoms is just an added bonus of vitamin B6. Not only does it lengthen the luteal phase, but it helps with the depression that sometimes accompanies pms. Aside from the benefits of treating PMS, vitamin B6's main role as a fertility vitamin is to treat the luteal phase defect (LPD).

A luteal phase defect is one cause of infertility, and is also one of the most easily treated. It occurs when the luteal phase (the time from ovulation to menstruation) is less than 10 days. Ideally, it would be best if this phase lasted 11-16 days. A luteal phase that is too short cannot maintain a pregnancy. If pregnancy occurs in a woman with LPD, the pregnancy can result in miscarriage.

A luteal phase defect can be detected by charting your basal body temperatures. This may take a month or two to catch on and figure out, but is worth while in determining if there is indeed a luteal phase problem. Once you determine this, then you can begin seeking help. And if you detect a luteal phase defect, one way of lengthening the luteal phase is with progesterone supplements. Another way of increasing the luteal phase is with vitamin B6.

While trying to conceive my third child, my luteal phase started out at 9 days. I checked my prenatal vitamin and it only had 3 mg of vitamin B6. This amount was insufficient to do any good. Very few multivitamins have a sufficient amount of vitamin B6 in each dose. Check the labels to be sure there is a sufficient amount of vitamin B6. I purchased a good B-complex vitamin with 60 mg of Vitamin B6, and this did wonders for my luteal phase. It went from 9 to 11 to 12 days in a matter of 2 months.

I've read it is recommended to take 100-200 mg of vitamin B6 a day to help with luteal phase defects. However, just 63 mg did the trick for me. Perhaps it would be smart to start out with smaller doses, to see if it would work. If the smaller amount doesn't work, you could simply increase your intake slowly. Vitamin B6 helps to normalize hormone levels, thus normalizing the luteal phase.

The advice presented in this article is not meant to diagnose or treat any condition. Check with your healthcare provider before taking any vitamins, or treating any conditions.

Lori Ramsey is a Mother and contributing writer for Baby Corner.

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Showing 1 - 10 out of 15 Comments
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Britishtink Dec 23, 2012 10:06:47 PM ET

Hi, I took vit B6 at 100mg for one cycle from the day my period ended and my luteal phase increased from 9 to 15 days...awesome!!

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patty Nov 15, 2012 09:34:24 AM ET

I have been on metformin for about four months when i discovered i had a short luteal phase. I started taking vit b6 and vit b12 and within one month my luteal phase is normal. it works!

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Dame Aug 13, 2012 11:49:22 PM ET

I v bn trying to conceive for d past 1yr 5months. My craps got worse in marriage. I v a cycle length of 25 days wit a short LP. Starting Vit B6 2day works like maggic for my cramps today and I av no nausea feelings again. I'm hoping it works for my 1st conception too.

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carol Jan 5, 2012 04:20:45 PM ET

I been taking 200mg b6 for a month now to help me with pms, I was wondering how long after words will I be able to conceive? Also I have very bad cramping and acne.

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Ophie Aug 29, 2011 11:00:33 PM ET

I realized I had a short luteal phase in May and started taking a B-complex vitamin once a day in June, it has worked. My last cycle was 27 days when it's normally 26 days with ovulation on the 14th or 15th cycle day. My ovulation was definitely on the 14th day last cycle and this cycle. AF is due tomorrow, but I've barely had any of my normal premenstrual cramping. Maybe conception has occurred, but if not, the vitamin B-complex has definitely helped in a short time.

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Tamela Jun 12, 2011 07:41:37 AM ET

Thank you for your information. I had a miscarriage back in January and after that life at work became extremely stressful. Which has thrown my body out of sorts. I don't like to take drugs and was looking for a natural way to help us try to get pregnant again. Thank you!

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Rebekah May 30, 2011 12:52:29 PM ET

B6 can be taking throughout the cycle to lengthen the luetal phase. 50mg can even be taken after pregnancy to help with morning sickness. I currently take 100mg daily, I am not pregnant. I have also read that B6 helps lessen the affects of endo.

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Trudy Dec 22, 2010 12:34:37 PM ET

I have a son who is taking 1000mg keppra morning and night and is so moody and violent i have heard b6 is good i have started b6 he is 100kilos how much should i give him and how long before it will take effect

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Trudy Dec 22, 2010 10:54:59 AM ET

I have a son who is taking 1000mg keppra morning and night and is so moody and violent i have heard b6 is good i have started b6 he is 100kilos how much should i give him and how long before it will take effect

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melanie Oct 16, 2010 12:37:06 PM ET

I took B6 while ttc. I got a positive blood test at the doctor on wednesday. Should I continue to take B6 after becoming pregnant? If so, for how long? I have been taking around 100 mg. Will this cause birth defects?

jesyca Oct 6, 2015 01:24:06 AM ET

How long did you take the b6 vitamin before you became pregnant?

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